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KMID : 1202020080010010074
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Journal of Korean Thyroid Association
2008 Volume.1 No. 1 p.74 ~ p.77
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A Case of Mixed Diffuse Large B-Cell Lymphoma and MALT Lymphoma of Thyroid Gland
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Shin Hyang-Ae
Han Jae-Ho
Kim Chul-Ho
Lee Jong-Joo
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Abstract
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Primary thyroid lymphoma is a rare thyroid tumor, representing approximately 2∼3% of all non-Hodgkin’s lymphoma (NHL) and 2∼8% of all thyroid malignancies. Thyroid lymphomas typically occur in middle- to older-aged women. Pathologically, most thyroid lymphomas are non-Hodgkin’s lymphomas of B-cell origin whereas Hodgkin’s and T-cell thyroid lymphomas occur rarely. Diffuse large B-cell lymphoma (DLBCL) is the most common histologic type followed by mucosa-associated lymphoid tissue (MALT) lymphoma. MALT lymphomas classically arise in a background of longstanding autoimmune thyroiditis. We report a case of mixed diffuse large B-cell lymphoma and MALT lymphoma of the thyroid gland accompanied by Hashimoto’s thyroiditis with a review of the literature.
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KEYWORD
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hyroid gland, Hashimoto’s thyroiditis, Mucosa-associated lymphoid tissue lymphoma, Diffuse large B-cell lymphoma
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